(S) -Laudanosine
(S) -Laudanosine is an alkaloid that can be found in poppies and is the S-enantiomer of Laudanosine. Laudanosine acts on the central nervous system and cardiovascular system, inhibiting low-affinity GABA receptors with an IC50 value of 10 μM, and can cause seizures, hypotension, and bradycardia. Additionally, Laudanosine exerts analgesic effects by competitively binding to the opioid Mu-1 receptor (Ki = 2.7 μM) [1][2][3][4].
Product Specifications
CAS Number
2688-77-9
UNSPSC
12352005
Hazard Statement
H301, H312, H330, H410
Target
GABA Receptor; Opioid Receptor
Type
Natural Products
Related Pathways
GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/s-laudanosine.html
Purity
99.95
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
CN1[C@H](C2=C(CC1)C=C(C(OC)=C2)OC)CC3=CC=C(C(OC)=C3)OC
Molecular Formula
C21H27NO4
Molecular Weight
357.44
Precautions
H301, H312, H330, H410
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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