Acetyl-Hirudin (54-65) (sulfated)
Product Specifications
UNSPSC Description
Acetyl-Hirudin (54-65) (sulfated) is a acetyl-fragment of Hirudin which binds directly to thrombin-rHCII(L444R) and disrupts interactions between the N-terminal acidic domain of rHCII and anion-binding exosite I of thrombin that serves to stabilize the complex[1].
Target Antigen
Others
Type
Peptides
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/acetyl-hirudin-54-65-sulfated.html
Solubility
H2O
Smiles
CC(NCC(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N2[C@@H](CCC2)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@H](C(N[C@@H](CC(C)C)C(N[C@H](C(O)=O)CCC(N)=O)=O)=O)CC3=CC=C(C=C3)OS(=O)(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Molecular Weight
1590.62
References & Citations
[1]J H Han, et al. Heparin facilitates dissociation of complexes between thrombin and a reactive site mutant (L444R) of heparin cofactor II. J Biol Chem. 1997 Mar 28;272(13):8243-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-P2490/Acetyl-Hirudin-54-65-sulfated-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P2490/
Clinical Information
No Development Reported
CAS Number
125441-00-1
Curated Selection
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