URAT1/GLUT9-IN-1
Product Specifications
UNSPSC Description
URAT1/GLUT9-IN-1 (compound 29) can inhibit both uric acid transporter 1 (URAT1) (IC50=2.01 μM) and glucose transporter 9 (GLUT9) (IC50=18.21 μM). URAT1/GLUT9-IN-1 exhibits favorable pharmacokinetic properties and oral bioavailability. URAT1/GLUT9-IN-1 can be uesd for gout and hyperuricemia research[1].
Target Antigen
GLUT; URAT1
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/urat1-glut9-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(O)CCCSC1=NC(NC2=C3C=CC=CC3=C(C4CC4)C=C2)=C5C(C=CS5)=N1
Molecular Weight
435.56
References & Citations
[1]Shi X, et al. Discovery of a Novel Thienopyrimidine Compound as a Urate Transporter 1 and Glucose Transporter 9 Dual Inhibitor with Improved Efficacy and Favorable Druggability[J]. Journal of Medicinal Chemistry, 2024, 67(6): 5032-5052.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158056/URAT1-GLUT9-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158056/
Clinical Information
No Development Reported
CAS Number
2883011-18-3
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Mouse Monoclonal Chromogranin A Antibody (SPM585) [DyLight 650]](https://cdn.genprice.uk/genprice/genprice5.png)
