Human FGF-8a (Fibroblast Growth Factor-8a)

<strong>Human FGF-8a (Fibroblast Growth Factor-8a)</strong>_x000D_ <strong>Catalog number:</strong> B2018629_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> ~21 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> FGF-8a, Fibroblast Growth Factor 8a_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Valve EM, Nevalainen MT, Nurmi MJ, Laato MK, Martikainen PM, Härkönen PL. Increased expression of FGF-8 isoforms and FGF receptors in human premalignant prostatic intraepithelial neoplasia lesions and prostate cancer Lab Invest. 2001 Jun;81(6):815-26._x000D_ 2: Adelfio M, Szymkowiak S, Kaplan DL. Matrigel-Free Laminin-Entactin Matrix to Induce Human Renal Proximal Tubule Structure Formation In Vitro ACS Biomater Sci Eng. 2020 Dec 14;6(12):6618-6625._x000D_ 3: Heinzle C, Erdem Z, Paur J, Grasl-Kraupp B, Holzmann K, Grusch M, Berger W, Marian B. Is fibroblast growth factor receptor 4 a suitable target of cancer therapy? Curr Pharm Des. 2014;20(17):2881-98._x000D_ 4: Gabler L, Jaunecker CN, Katz S, van Schoonhoven S, Englinger B, Pirker C, Mohr T, Vician P, Stojanovic M, Woitzuck V, Laemmerer A, Kirchhofer D, Mayr L, LaFranca M, Erhart F, Grissenberger S, Wenninger-Weinzierl A, Sturtzel C, Kiesel B, Lang A, Marian B, Grasl-Kraupp B, Distel M, Schüler J, Gojo J, Grusch M, Spiegl-Kreinecker S, Donoghue DJ, Lötsch D, Berger W. Fibroblast growth factor receptor 4 promotes glioblastoma progression: a central role of integrin-mediated cell invasiveness Acta Neuropathol Commun. 2022 Apr 28;10(1):65._x000D_ 5: Chan SJ, Love C, Spector M, Cool SM, Nurcombe V, Lo EH. Endogenous regeneration: Engineering growth factors for stroke Neurochem Int. 2017 Jul;107:57-65._x000D_ 6: Tanaka A, Furuya A, Yamasaki M, Hanai N, Kuriki K, Kamiakito T, Kobayashi Y, Yoshida H, Koike M, Fukayama M. High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing monoclonal antibody against FGF 8 Cancer Res. 1998 May 15;58(10):2053-6._x000D_ 7: Miura K, Miura S, Yoshiura K, Seminara S, Hamaguchi D, Niikawa N, Masuzaki H. A case of Kallmann syndrome carrying a missense mutation in alternatively spliced exon 8A encoding the immunoglobulin-like domain IIIb of fibroblast growth factor receptor 1 Hum Reprod. 2010 Apr;25(4):1076-80._x000D_ 8: Harpain F, Ahmed MA, Hudec X, Timelthaler G, Jomrich G, Müllauer L, Selzer E, Dörr W, Bergmann M, Holzmann K, Grasl-Kraupp B, Grusch M, Berger W, Marian B, Silberhumer GR. FGF8 induces therapy resistance in neoadjuvantly radiated rectal cancer J Cancer Res Clin Oncol. 2019 Jan;145(1):77-86._x000D_ 9: Ling L, Ren X, Cao X, Hassan ABM, Mah S, Sathiyanathan P, Smith RAA, Tan CLL, Eio M, Samsonraj RM, van Wijnen AJ, Raghunath M, Nurcombe V, Hui JH, Cool SM. Enhancing the Efficacy of Stem Cell Therapy with Glycosaminoglycans Stem Cell Reports. 2020 Jan 14;14(1):105-121._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/12213878">10: McCabe CJ, Boelaert K, Tannahill LA, Heaney AP, Stratford AL, Khaira JS, Hussain S, Sheppard MC, Franklyn JA, Gittoes NJ. Vascular endothelial growth factor, its receptor KDR/Flk-1, and pituitary tumor transforming gene in pituitary tumors J Clin Endocrinol Metab. 2002 Sep;87(9):4238-44. </a>_x000D_ _x000D_ <strong>Products Related to Human FGF-8a (Fibroblast Growth Factor-8a) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>