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GARP&Latent TGF Beta Complex, Human (HEK293, His-Avi)

LRRC32 is a key regulator of TGF-β activation and maintains TGFB1, TGFB2, and TGFB3 in the latent state during extracellular storage by binding to latency-associated peptide (LAP) . LRRC32 competes with LTBP1 for LAP binding and effectively regulates integrin-dependent TGF-β activation. GARP&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi) is a recombinant protein dimer complex containing human-derived GARP&Latent TGF Beta Complex protein, expressed by HEK293 , with C-Avi, C-His labeled tag. GARP&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi), has molecular weight of 72-80 kDa.

Product Specifications

Product Name Alternative

GARP&Latent TGF Beta Complex Protein, Human (HEK293, His-Avi), Human, HEK293

UNSPSC

12352202

Type

Recombinant Proteins

Assay Protocol

https://www.medchemexpress.com/cytokines/garp-latent-tgf-beta-complex-protein-human-hek293-his-avi.html

Molecular Formula

2615&7040 (Gene_ID) Q14392 (H20-L628) &P01137 (L30-S390) (Accession)

Molecular Weight

Approximately 72-80 kDa (GARP) & 13 kDa & 42-50 kDa (Latent TGF beta 1), based on SDS-PAGE under reducing conditions, due to the glycosylation.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

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