Human Cardiac Tropomyosin

<strong>Human Cardiac Tropomyosin</strong>_x000D_ <strong>Catalog number:</strong> B2018434_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 0.1 mg_x000D_ <strong>Molecular Weight or Concentration:</strong> N/A_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong>  -20°C_x000D_ <strong>Keywords:</strong> Human Cardiac Tropomyosin_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Cai W, Xu D, Zeng C, Liao F, Li R, Lin Y, Zhao Y, Dong W, Wang Q, Yang H, Wen D, Gu J, Shentu W, Yu H, Zhang X, Wei J, Duan J. Modulating Lysine Crotonylation in Cardiomyocytes Improves Myocardial Outcomes Circ Res. 2022 Aug 19;131(5):456-472._x000D_ 2: Doran MH, Rynkiewicz MJ, Rasicci D, Bodt SML, Barry ME, Bullitt E, Yengo CM, Moore JR, Lehman W. Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin J Gen Physiol. 2023 Mar 6;155(3):e202213267._x000D_ 3: El-Mezgueldi M. Tropomyosin dynamics J Muscle Res Cell Motil. 2014 Aug;35(3-4):203-10._x000D_ 4: Cummins P, McGurk B, Littler WA. Radioimmunoassay of human cardiac tropomyosin in acute myocardial infarction Clin Sci (Lond). 1981 Mar;60(3):251-9._x000D_ 5: Matyushenko AM, Nefedova VV, Kochurova AM, Kopylova GV, Koubassova NA, Shestak AG, Yampolskaya DS, Shchepkin DV, Kleymenov SY, Ryabkova NS, Katrukha IA, Bershitsky SY, Zaklyazminskaya EV, Tsaturyan AK, Levitsky DI. Novel Mutation Glu98Lys in Cardiac Tropomyosin Alters Its Structure and Impairs Myocardial Relaxation Int J Mol Sci. 2023 Aug 2;24(15):12359._x000D_ 6: Loong CK, Zhou HX, Chase PB. Persistence length of human cardiac α-tropomyosin measured by single molecule direct probe microscopy PLoS One. 2012;7(6):e39676._x000D_ 7: McConnell M, Tal Grinspan L, Williams MR, Lynn ML, Schwartz BA, Fass OZ, Schwartz SD, Tardiff JC. Clinically Divergent Mutation Effects on the Structure and Function of the Human Cardiac_Tropomyosin Overlap Biochemistry. 2017 Jul 5;56(26):3403-3413._x000D_ 8: Bing W, Knott A, Redwood C, Esposito G, Purcell I, Watkins H, Marston S. Effect of hypertrophic cardiomyopathy mutations in human cardiac muscle alpha -tropomyosin (Asp175Asn and Glu180Gly) on the regulatory properties of human cardiac troponin determined by in vitro motility assay J Mol Cell Cardiol. 2000 Aug;32(8):1489-98._x000D_ 9: Vanburen P, Palmer BM. Cooperative activation of the cardiac myofilament: the pivotal role of tropomyosin Circulation. 2010 Jan 26;121(3):351-3._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/36884028">10: Cannavo A, Jun S, Rengo G, Marzano F, Agrimi J, Liccardo D, Elia A, Keceli G, Altobelli GG, Marcucci L, Megighian A, Gao E, Feng N, Kammers K, Ferrara N, Finos L, Koch WJ, Paolocci N. β3AR-Dependent Brain-Derived Neurotrophic Factor (BDNF) Generation Limits Chronic Postischemic Heart Failure Circ Res. 2023 Mar 31;132(7):867-881. </a>_x000D_ _x000D_ <strong>Products Related to Human Cardiac Tropomyosin can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>