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L-697639

Product Specifications

UNSPSC Description

L-697639 is an inhibitor for HIV-1 reverse transcriptase (HIV-1 RT) with IC50 of 20-400 nM (in a template-primer-dependent manner). L-697639 exhibits antiviral activity, that inhibits 95% HIV-1 infection at concentrations of 12-200 nM in human T lymphocyte cultures[1].

Target Antigen

HIV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/l-697639.html

Smiles

O=C1C(NCC2=NC3=C(C)C=CC(C)=C3O2)=CC(CC)=C(C)N1

Molecular Weight

311.38

References & Citations

[1]Goldman ME, et al. Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity. Proc Natl Acad Sci U S A. 1991 Aug 1;88(15):6863-7.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-19143/L-697639-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-19143/

Clinical Information

Phase 1

CAS Number

135525-77-8

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