L-697639

L-697639 is an inhibitor for HIV-1 reverse transcriptase (HIV-1 RT) with IC50 of 20-400 nM (in a template-primer-dependent manner) . L-697639 exhibits antiviral activity, that inhibits 95% HIV-1 infection at concentrations of 12-200 nM in human T lymphocyte cultures[1].

Product Specifications

CAS Number

[135525-77-8]

UNSPSC

12352005

Target

HIV

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/l-697639.html

Smiles

O=C1C(NCC2=NC3=C(C)C=CC(C)=C3O2)=CC(CC)=C(C)N1

Molecular Formula

C18H21N3O2

Molecular Weight

311.38

References & Citations

[1]Goldman ME, et al. Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity. Proc Natl Acad Sci U S A. 1991 Aug 1;88 (15) :6863-7.