L-697639
L-697639 is an inhibitor for HIV-1 reverse transcriptase (HIV-1 RT) with IC50 of 20-400 nM (in a template-primer-dependent manner) . L-697639 exhibits antiviral activity, that inhibits 95% HIV-1 infection at concentrations of 12-200 nM in human T lymphocyte cultures[1].
Product Specifications
CAS Number
135525-77-8
UNSPSC
12352005
Target
HIV
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/l-697639.html
Smiles
O=C1C(NCC2=NC3=C(C)C=CC(C)=C3O2)=CC(CC)=C(C)N1
Molecular Formula
C18H21N3O2
Molecular Weight
311.38
References & Citations
[1]Goldman ME, et al. Pyridinone derivatives: specific human immunodeficiency virus type 1 reverse transcriptase inhibitors with antiviral activity. Proc Natl Acad Sci U S A. 1991 Aug 1;88 (15) :6863-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
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