IREB2 Recombinant Mouse Monoclonal Antibody [9D1-R]
RNA-binding protein that binds to iron-responsive elements (IRES), which are stem-loop structures found in the 5'-UTR of ferritin, and delta aminolevulinic acid synthase mRNAs, and in the 3'-UTR of transferrin receptor mRNA. Binding to the IRE element in ferritin results in the repression of its mRNA translation. Binding of the protein to the transferrin receptor mRNA inhibits the degradation of this otherwise rapidly degraded mRNA.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
Iron-responsive element-binding protein 2 IRE-BP 2 Iron regulatory protein 2 IRP2
Swiss Prot
P48200 Human, Q811J3 Mouse, Q62751 Rat
Cellular Locus
Cytoplasm.
Host
Mouse
Species Reactivity
Human,Mouse,Rat
Immunogen
Recombinant protein within human IREB2 aa 1-963.
Isotype
IgG1
Clone
9D1-R
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB
Positive Control
Jurkat cell lysate, A549 cell lysate, Mouse liver tissue lysate, Mouse kidney tissue lysate, Mouse heart tissue lysate, Rat liver tissue lysate.
Concentration
1 mg/mL
Dilution
WB: 1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 105 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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