Protoplumericin A
Protoplumericin A is a bioactive ingredient of Plumeria obtusa L. attenuates. Protoplumericin A mitigated lipopolysaccharide (LPS) -induced acute lung injury in mice. Protoplumericin A can be used to study the LPS-induced anti-inflammatory effect [1].
Product Specifications
CAS Number
80396-57-2
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/protoplumericin-a.html
Solubility
10 mM in DMSO
Smiles
O[C@H]([C@@H](O)[C@@H]1O)[C@](O[C@@H]1CO)([H])O[C@H](OC=C(C(OC)=O)[C@@]2([H])C=C3)[C@]2([H])[C@]3(O4)C=C([C@H](C)OC(/C=C/C5=CC=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]6O)O)O[C@@H]6CO)C=C5)=O)C4=O
Molecular Formula
C36H42O19
Molecular Weight
778.71
References & Citations
[1]Eloutify YT, El-Shiekh RA, Ibrahim KM, Hamed AR, Al-Karmalawy AA, Shokry AA, Ahmed YH, Avula B, Katragunta K, Khan IA, Meselhy MR. Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking. Inflammopharmacology. 2023 Apr;31 (2) :859-875.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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