Protoplumericin A

Protoplumericin A is a bioactive ingredient of Plumeria obtusa L. attenuates. Protoplumericin A mitigated lipopolysaccharide (LPS) -induced acute lung injury in mice. Protoplumericin A can be used to study the LPS-induced anti-inflammatory effect [1].

Product Specifications

CAS Number

[80396-57-2]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/protoplumericin-a.html

Solubility

10 mM in DMSO

Smiles

O[C@H]([C@@H](O)[C@@H]1O)[C@](O[C@@H]1CO)([H])O[C@H](OC=C(C(OC)=O)[C@@]2([H])C=C3)[C@]2([H])[C@]3(O4)C=C([C@H](C)OC(/C=C/C5=CC=C(O[C@@H]([C@@H]([C@@H](O)[C@@H]6O)O)O[C@@H]6CO)C=C5)=O)C4=O

Molecular Formula

C36H42O19

Molecular Weight

778.71

References & Citations

[1]Eloutify YT, El-Shiekh RA, Ibrahim KM, Hamed AR, Al-Karmalawy AA, Shokry AA, Ahmed YH, Avula B, Katragunta K, Khan IA, Meselhy MR. Bioactive fraction from Plumeria obtusa L. attenuates LPS-induced acute lung injury in mice and inflammation in RAW 264.7 macrophages: LC/QToF-MS and molecular docking. Inflammopharmacology. 2023 Apr;31 (2) :859-875.