3-Methyl-4-nitrophenol

3-Methyl-4-nitrophenol, an environmental contaminant, is a well-known constituent of diesel exhaust particles and degradation products of insecticide fenitrothion. 3-Methyl-4-nitrophenol can induce nasal epithelial cell apoptosis and increase the permeability of the nasal epithelial barrier. 3-Methyl-4-nitrophenol is also toxic to the female reproductive system.

Product Specifications

CAS Number

[2581-34-2]

UNSPSC

12352005

Hazard Statement

H302, H312, H315, H319, H332, H335

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-methyl-4-nitrophenol.html

Purity

99.70

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC1=CC=C([N+]([O-])=O)C(C)=C1

Molecular Formula

C7H7NO3

Molecular Weight

153.14

Precautions

H302, H312, H315, H319, H332, H335

References & Citations

[1]Fan S, et, al. The effect of 3-Methyl-4-Nitrophenol on the early ovarian follicle development in mice by disrupting the clock genes expression. Chem Biol Interact. 2022 Aug 25:363:110001.|[2]An YF, et, al. The 3-methyl-4-nitrophenol (PNMC) compromises airway epithelial barrier function. Toxicology. 2018 Feb 15:395:9-14.