mPGES1-IN-4
Product Specifications
UNSPSC Description
mPGES1-IN-4 (compound 32) is a polysubstituted pyrimidine compound and a submicromolar PGE2 production inhibitor. It exerts its anti-inflammatory effect mainly by inhibiting mPGES-1 and has a significant inhibitory effect on the acute inflammation model in vivo.
Target Antigen
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/mpges1-in-4.html
Smiles
FC1=C(OCC2=CC=CC=C2)C=CC(C3=C(CCCC)C(C4=CC=CC=C4)=NC(N)=N3)=C1F
Molecular Weight
445.50
References & Citations
[1]Polysubstituted Pyrimidines as mPGES-1 Inhibitors: Discovery of Potent Inhibitors of PGE2 Production with Strong Anti-inflammatory Effects in Carrageenan-Induced Rat Paw Edema
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-139364/mPGES1-IN-4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-139364/
Clinical Information
Phase 4
CAS Number
2253745-78-5
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
