Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

MPGES1-IN-4

MPGES1-IN-4 (compound 32) is a polysubstituted pyrimidine compound and a submicromolar PGE2 production inhibitor. It exerts its anti-inflammatory effect mainly by inhibiting mPGES-1 and has a significant inhibitory effect on the acute inflammation model in vivo.

Product Specifications

CAS Number

[2253745-78-5]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

PGE synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/mpges1-in-4.html

Smiles

FC1=C(OCC2=CC=CC=C2)C=CC(C3=C(CCCC)C(C4=CC=CC=C4)=NC(N)=N3)=C1F

Molecular Formula

C27H25F2N3O

Molecular Weight

445.50

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Polysubstituted Pyrimidines as mPGES-1 Inhibitors: Discovery of Potent Inhibitors of PGE2 Production with Strong Anti-inflammatory Effects in Carrageenan-Induced Rat Paw Edema

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 4

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

IGFBP7 protein, Human, Recombinant (His)
E51P91094 20 µg

IGFBP7 protein, Human, Recombinant (His)

Ask
View Details
Human Monoclonal IL-18/IL-1F4 Antibody (GSK 1070806) [DyLight 650]
NBP3-27989C 0.1 mL

Human Monoclonal IL-18/IL-1F4 Antibody (GSK 1070806) [DyLight 650]

Ask
View Details
DTL Antibody
DF15736-01 100 µL

DTL Antibody

Ask
View Details
DTL Antibody
DF15736-02 200 µL

DTL Antibody

Ask
View Details
LXN Polyclonal Antibody
E-AB-10437-01 20 µL

LXN Polyclonal Antibody

Ask
View Details
LXN Polyclonal Antibody
E-AB-10437-02 60 μL

LXN Polyclonal Antibody

Ask
View Details