Bcl-2-IN-21
Bcl-2-IN-21 (compound C1) is an iridium compound with anticancer activity that targets and inhibits Bcl-2. Bcl-2-IN-21 inhibits colony formation of cancer cells and induces elevated levels of Bax and caspase 3[1].
Product Specifications
UNSPSC
12352005
Target
Bcl-2 Family
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bcl-2-in-21.html
Smiles
FP(F)(F)(F)(F)F.C1(C=CC=C2)=[N]2[Ir]34([N]5=C(C6=[N]4C(C=CC=C7)=C7N6CC8=CC=CC=C8)C=CC9=CC=CC=C59)([N]%10=C(C=CC=C%10)C%11=CC=CC=C%113)C%12=CC=CC=C1%12
Molecular Formula
C45H33F6IrN5P
Molecular Weight
980.96
References & Citations
[1]New cyclometalated iridium (III) complexes bearing substituted 2- (1H-benzimidazol-2-yl) quinoline: Synthesis, characterization, electrochemical and anticancer studies
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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