Rabbit polyclonal antibodies to Morphine

Morphine, the most powerful opiate analgesic drug in opium, acts directly on synapses of the arcuate nuclei within the central nervous system to relieve pain. It is a highly addictive drug, to which tolerance as well as physical and psychological dependences quickly develop. Administered as intravenous, subcutaneous or epidural injections, Morphine creates a profound contraction sensation in the muscles due to histamine release and also produces a "rush" mediated by different receptors in the central nervous system. Morphine is a phenanthrene opioid receptor agonist. By binding to μ opioid receptors within the central nervous system associated with analgesia, sedation, physical dependence and respiratory depression, the euphoric effects of Morphine are quickly followed by withdrawal symptoms.