AC4
AC4 is a trans antagonist upon voltageactivation of TRPV1 and as cis antagonist of TRPV1 currents upon stimulation with Capsaicin (HY-10448) . AC4 demonstrates that a photoswitchable antagonist and an agonist can be used in concert[1].
Product Specifications
CAS Number
[1459809-09-6]
UNSPSC
12352005
Target
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac4.html
Smiles
S=C(N1CCCC2=CC(O)=C(O)C=C2C1)NCCC3=CC=C(/N=N/C4=CC=C(C(F)(F)F)C=C4)C=C3
Molecular Formula
C26H25F3N4O2S
Molecular Weight
514.56
References & Citations
[1]Stein M, et al. Optical control of TRPV1 channels. Angew Chem Int Ed Engl. 2013 Sep 9;52 (37) :9845-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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