AC4
Product Specifications
UNSPSC Description
AC4 is a trans antagonist upon voltageactivation of TRPV1 and as cis antagonist of TRPV1 currents upon stimulation with Capsaicin (HY-10448). AC4 demonstrates that a photoswitchable antagonist and an agonist can be used in concert[1].
Target Antigen
TRP Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel;Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac4.html
Smiles
S=C(N1CCCC2=CC(O)=C(O)C=C2C1)NCCC3=CC=C(/N=N/C4=CC=C(C(F)(F)F)C=C4)C=C3
Molecular Weight
514.56
References & Citations
[1]Stein M, et al. Optical control of TRPV1 channels. Angew Chem Int Ed Engl. 2013 Sep 9;52(37):9845-8.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-110209/AC4-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-110209/
Clinical Information
No Development Reported
CAS Number
1459809-09-6
Curated Selection
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