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AC4

Product Specifications

UNSPSC Description

AC4 is a trans antagonist upon voltageactivation of TRPV1 and as cis antagonist of TRPV1 currents upon stimulation with Capsaicin (HY-10448). AC4 demonstrates that a photoswitchable antagonist and an agonist can be used in concert[1].

Target Antigen

TRP Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel;Neuronal Signaling

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac4.html

Smiles

S=C(N1CCCC2=CC(O)=C(O)C=C2C1)NCCC3=CC=C(/N=N/C4=CC=C(C(F)(F)F)C=C4)C=C3

Molecular Weight

514.56

References & Citations

[1]Stein M, et al. Optical control of TRPV1 channels. Angew Chem Int Ed Engl. 2013 Sep 9;52(37):9845-8.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-110209/AC4-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-110209/

Clinical Information

No Development Reported

CAS Number

1459809-09-6

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