Fasedienol
Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON) . Fasedienol significantly increases Ca++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety[1][2][3].
Product Specifications
CAS Number
23062-06-8
Product Name Alternative
PH94B
UNSPSC
12352211
Hazard Statement
H302, H315, H319, H335
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fasedienol.html
Concentration
10mM
Purity
99.68
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
C[C@@]12[C@]3([H])[C@](CCC1=C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(C=CC4)C
Molecular Formula
C19H28O
Molecular Weight
272.43
Precautions
H302, H315, H319, H335
References & Citations
[1]Clive L. Jennings-White, et al. Steroids as neurochemical stimulators of the vno to alleviate symptoms of anxiety. Patent WO1998014194A1.|[2]Monti L, et al. Effect of fasedienol (PH94B) pherine nasal spray and steroidal hormones on electrogram responses and autonomic nervous system activity in healthy adult volunteers[J]. Human Psychopharmacology: Clinical and Experimental, 2024, 39 (2) : e2892.|[3]Monti L, et al. Neural circuits of anxiolytic and antidepressant pherine molecules. CNS Spectr. 2022 Feb;27 (1) :66-72.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3
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