Fasedienol

Fasedienol (PH94B) is a neurochemical stimulator of the vomeronasal organ (VON) . Fasedienol significantly increases Ca++. Fasedienol modulates the olfactory amygdala circuitry of fear and anxiety to alleviate symptoms of PMS and anxiety[1][2][3].

Product Specifications

CAS Number

[23062-06-8]

Product Name Alternative

PH94B

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fasedienol.html

Concentration

10mM

Purity

99.68

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

C[C@@]12[C@]3([H])[C@](CCC1=C[C@H](CC2)O)([H])[C@@]4([H])[C@](CC3)(C=CC4)C

Molecular Formula

C19H28O

Molecular Weight

272.43

Precautions

H302, H315, H319, H335

References & Citations

[1]Clive L. Jennings-White, et al. Steroids as neurochemical stimulators of the vno to alleviate symptoms of anxiety. Patent WO1998014194A1.|[2]Monti L, et al. Effect of fasedienol (PH94B) pherine nasal spray and steroidal hormones on electrogram responses and autonomic nervous system activity in healthy adult volunteers[J]. Human Psychopharmacology: Clinical and Experimental, 2024, 39 (2) : e2892.|[3]Monti L, et al. Neural circuits of anxiolytic and antidepressant pherine molecules. CNS Spectr. 2022 Feb;27 (1) :66-72.