DDHF20
DDHF20 is an antimicrobial agent against Staphylococcus aureus, targeting and inhibiting its thioredoxin reductase (TrxR) . It acts as a competitive inhibitor for the NADPH binding site. DDHF20 is expected to be used in research related to antimicrobial infections caused by Staphylococcus aureus[1].
Product Specifications
UNSPSC
12352211
Target
TrxR
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ddhf20.html
Smiles
O=C(C1OC(CC(C)(C)CC2=O)=C2C1C3=C(C=CC4=C5C(C=C6)=CC=C4)C5=C6C=C3)C7=CC=C(OC)C=C7
Molecular Formula
C34H28O4
Molecular Weight
500.58
References & Citations
[1]Shukla M, et al. One-Pot Green Synthesis and Biological Evaluation of Dimedone-Coupled 2,3-Dihydrofuran Derivatives to Divulge Their Inhibition Potential against Staphylococcal Thioredoxin Reductase Enzyme. ACS Omega. 2024 Oct 21;9 (43) :43414-43425.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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