(R) -Coriolic acid
(R) -Coriolic acid (13 (R) -HODE) is the opposite enantiomer of the 13 (S) -HODE produced when linoleic acid is incubated with soybean lipoxygenase. The presence of 13 (R) -HODE in the supernatants and membranes of cultured bovine endothelial cells has been attributed to COX metabolism. 13 (R) -HODE is a weak (IC50=2.7 μM) inhibitor of U-46619-induced platelet aggregation.
Product Specifications
CAS Number
[10219-69-9]
Product Name Alternative
13 (R) -HODE
UNSPSC
12352211
Hazard Statement
H225-H319
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/r-coriolic-acid.html
Smiles
CCCCC[C@@H](O)/C=C/C=C\CCCCCCCC(O)=O
Molecular Formula
C18H32O3
Molecular Weight
296.44
Precautions
P210-P233-P240-P241-P242-P243-P264-P280-P303+P361+P353-P305+P351+P338-P370+P378-P403+P235-P501
References & Citations
[1]Lagarde, et al. Further studies on the anti-thromboxane A2 activity of monohydroxylated fatty acids. Biochem. Pharmacol. 38, 1863-1864 (1989) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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