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Mutant p53 modulator-1

Mutant p53 modulator-1 is a mutant p53 modulator. Mutant p53 modulator-1 reduces the progression of cancers that contain a p53 mutation (extracted from patent WO2021231474A1, compound 231B) [1].

Product Specifications

CAS Number

[2746371-35-5]

UNSPSC

12352005

Target

MDM-2/p53

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mutant-p53-modulator-1.html

Purity

99.89

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

FC(F)(F)CN1C2=CC=CC(N[C@H]3[C@H](CN(CC3)C)F)=C2C=C1C4=NOC(CNC(C5=CN(N=C5)C(C)(C)C)=O)=N4

Molecular Formula

C27H32F4N8O2

Molecular Weight

576.59

References & Citations

[1]Binh Vu, et al. METHODS AND COMPOUNDS FOR RESTORING MUTANT p53 FUNCTION. Patent WO2021231474A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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