Cixutumumab Antibody
Cixutumumab (IMC-A12) is a human IgG1 monoclonal antibody that binds to and blocks the insulin-like growth factor 1 receptor (IGF1R) . It inhibits IGF1-mediated signaling and demonstrates antitumor activity, making it a valuable research tool for studying cancers such as non-small cell lung cancer and prostate cancer in both in vitro and in vivo models.
Product Specifications
Product Name Alternative
Cixutumumab, IMCA12, IMC-A12, NSC 742460, LY 3012217, LY3012217, NSC742460, NSC-742460, IGF1R, IGF-1R
Target
IGF-1R
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Concentration
7.13 mg/mL
Purity
97.50% (May vary between batches)
Molecular Weight
146.32 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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