Tanezumab Antibody
Tanezumab is a humanized monoclonal antibody that alleviates pain by selectively targeting nerve growth factor (NGF) . It blocks NGF's interaction with its TrkA and p75 receptors, inhibiting pain signal transduction. This mechanism has been investigated in preclinical models and clinical trials for conditions like osteoarthritis and chronic neuropathic pain.
Product Specifications
Product Name Alternative
PF-4383119, RN 624, Tanezumab
Target
Trk receptor
Clonality
Monoclonal
Conjugation
Unconjugated
Field of Research
Signal Transduction
Concentration
5.51 mg/mL
Purity
95.00% (May vary between batches)
Molecular Weight
145.43 kDa
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Notes
For research use only.
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