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Letaplimab Antibody

Letaplimab (IBI-188) is a humanized anti-CD47 IgG4 monoclonal antibody. It is investigated in combination with azacitidine for intermediate- to high-risk MDS, with research demonstrating its role in blocking the "don't eat me" signal to promote macrophage-mediated phagocytosis of cancer cells in preclinical models.

Product Specifications

Product Name Alternative

CD47, IBI 188, IBI188, IBI-188, Letaplimab

Target

Others

Conjugation

Unconjugated

Concentration

17.13 mg/mL

Purity

>95.0% (May vary between batches)

Molecular Weight

142.38 kDa

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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