Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

One-step TUNEL In Situ Apoptosis Kit (Red, Elab Fluor® 555)

Product Specifications

Detection Method

Fluorometric method

Assay Principle

When cells undergo apoptosis, specific DNA endonucleases will be activated, cutting the genomic DNA between the nucleosomes. The DNA of apoptotic cells is cleaved into multimers of 180~200bp fragments, corresponding to the oligonucleosomal size. Therefore, the DNA of apoptotic cells typically migrates as a ladder of 180~200bp on an agarose gel. The exposed 3'-OH of the broken DNA can be catalyzed by Terminal Deoxynucleotidyl Transferase (TdT) with fluorescein labeled dUTP, which can be detected with fluorescence microscope.

Sample Type

Paraffin section; frozen section; cell slide

Shipping Conditions

Ice bag

Storage Conditions

This product can be stored at -20°C for 12 months with shading light.

Product Datasheet

https://789.bio/ea/98ubfd

Product MSDS

https://789.bio/eb/n5eTGS

Citation 01

https://www.science.org/doi/abs/10.1126/sciimmunol.adc9081

Citation 02

https://aacrjournals.org/cancerres/article/doi/10.1158/0008-5472.CAN-23-2491/735128

Citation 03

https://www.nature.com/articles/s41401-023-01218-z

Citation 04

https://biosignaling.biomedcentral.com/articles/10.1186/s12964-024-01479-z

Citation 05

https://www.ahajournals.org/doi/abs/10.1161/ATVBAHA.123.319119

Citation 06

https://www.nature.com/articles/s41420-023-01740-3

Citation 07

https://www.sciencedirect.com/science/article/pii/S0891584924011298

Citation 08

https://onlinelibrary.wiley.com/doi/abs/10.1002/glia.24449

Citation 09

https://pmc.ncbi.nlm.nih.gov/articles/PMC12147254/

Citation 10

https://journals.physiology.org/doi/abs/10.1152/ajpcell.00348.2023

Citation 11

https://www.mdpi.com/1422-0067/24/13/11210

Citation 12

https://www.sciencedirect.com/science/article/pii/S1567576924000158

Detection Instrument

Fluorescence Microscope

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Rabbit Monoclonal PD-ECGF/Thymidine Phosphorylase Antibody (TYMP/2890R) [Janelia Fluor 646]
NBP3-08402JF646 100 µL

Rabbit Monoclonal PD-ECGF/Thymidine Phosphorylase Antibody (TYMP/2890R) [Janelia Fluor 646]

Ask
View Details
AGR2, ID (Anterior Gradient Protein 2 Homolog, Secreted Cement Gland Protein XAG-2 Homolog, AG-2, hAG-2, HPC8, AG2, Anterior Gradient 2, UNQ515/PRO1030) (Azide free) (HRP)
MBS6463300-01 0.2 mL

AGR2, ID (Anterior Gradient Protein 2 Homolog, Secreted Cement Gland Protein XAG-2 Homolog, AG-2, hAG-2, HPC8, AG2, Anterior Gradient 2, UNQ515/PRO1030) (Azide free) (HRP)

Ask
View Details
AGR2, ID (Anterior Gradient Protein 2 Homolog, Secreted Cement Gland Protein XAG-2 Homolog, AG-2, hAG-2, HPC8, AG2, Anterior Gradient 2, UNQ515/PRO1030) (Azide free) (HRP)
MBS6463300-02 5x 0.2 mL

AGR2, ID (Anterior Gradient Protein 2 Homolog, Secreted Cement Gland Protein XAG-2 Homolog, AG-2, hAG-2, HPC8, AG2, Anterior Gradient 2, UNQ515/PRO1030) (Azide free) (HRP)

Ask
View Details
ZNF440 Antibody
DF2432-01 100 µL

ZNF440 Antibody

Ask
View Details
ZNF440 Antibody
DF2432-02 200 µL

ZNF440 Antibody

Ask
View Details
Kinesin Family Member 1C (KIF1C) Antibody
abx146469-01 100 µg

Kinesin Family Member 1C (KIF1C) Antibody

Ask
View Details