Glabrolide
Product Specifications
UNSPSC Description
Glabrolide, derived from Glycyrrhiza uralensis Fisch., is a β-secretase 1 (BACE-1) inhibitor[1].
Target Antigen
Beta-secretase
Type
Natural Products
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/glabrolide.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@@](C(C=C3[C@]2(CC[C@]4(C)[C@@]3([H])C[C@]5(C)C[C@@]4([H])OC5=O)C)=O)([H])[C@@]6([C@@](C(C)([C@@H](O)CC6)C)([H])CC1)C
Molecular Weight
468.67
References & Citations
[1]Arif N, et al. In silico Inhibition of BACE-1 by Selective Phytochemicals as Novel Potential Inhibitors: Molecular Docking and DFT Studies. Curr Drug Discov Technol. 2019 Feb 14.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N4186/Glabrolide-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N4186/
Clinical Information
No Development Reported
CAS Number
10401-33-9
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