Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Laquinimod (Standard)

Laquinimod (Standard) is the analytical standard of Laquinimod. This product is intended for research and analytical applications. Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research[1][2][3][4].

Product Specifications

CAS Number

248281-84-7

Product Name Alternative

ABR-215062 (Standard)

UNSPSC

12352005

Target

Apoptosis; NF-κB; Reference Standards

Type

Reference Standards

Related Pathways

Apoptosis; NF-κB; Others

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/laquinimod-standard.html

Smiles

O=C(C1=C(O)C2=C(N(C)C1=O)C=CC=C2Cl)N(CC)C3=CC=CC=C3

Molecular Formula

C19H17ClN2O3

Molecular Weight

356.80

References & Citations

[1]Schulze-Topphoff, Ulf., et al. Laquinimod, a quinoline-3-carboxamide, induces type II myeloid cells that modulate central nervous system autoimmunity. PLoS One (2012), 7 (3), e33797.|[2]Toubi E, et al. Laquinimod modulates B cells and their regulatory effects on T cells in Multiple Sclerosis. J Neuroimmunol. 2012 Oct 15;251 (1-2) :45-54.|[3]Brück W, et al. Reduced astrocytic NF-κB activation by laquinimod protects from cuprizone-induced demyelination. Acta Neuropathol. 2012 Sep;124 (3) :411-24.|[4]Jan Thöne, et al. Laquinimod in the treatment of multiple sclerosis: a review of the data so far. Drug Des Devel Ther. 2016 Mar 14;10:1111-8.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Recombinant Rat MIF Protein (Gst Tag)
PDER100139-01 20 µg

Recombinant Rat MIF Protein (Gst Tag)

Sign In for Pricing
View Details
Recombinant Rat MIF Protein (Gst Tag)
PDER100139-02 100 µg

Recombinant Rat MIF Protein (Gst Tag)

Sign In for Pricing
View Details
Recombinant Rat MIF Protein (Gst Tag)
PDER100139-03 500 µg

Recombinant Rat MIF Protein (Gst Tag)

Sign In for Pricing
View Details
Recombinant Rat MIF Protein (Gst Tag)
PDER100139-04 1 mg

Recombinant Rat MIF Protein (Gst Tag)

Sign In for Pricing
View Details
1,2-Dioleoyl-3-stearoyl-rac-glycerol
TRC-D484300-50MG 50 mg

1,2-Dioleoyl-3-stearoyl-rac-glycerol

Sign In for Pricing
View Details
UCK (UCK1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1A12]
TA501542BM 100 µL

UCK (UCK1) Mouse Monoclonal Antibody (HRP conjugated) [Clone ID: OTI1A12]

Sign In for Pricing
View Details