Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Minodronic acid-d4

Minodronic acid-d4 is deuterium labeled Minodronic acid. Minodronic acid (YM-529) is a third-generation bisphosphonate that directly and indirectly prevents proliferation, induces apoptosis, and inhibits metastasis of various types of cancer cells. Minodronic acid (YM-529) is an antagonist of purinergic P2X2/3 receptors involved in pain[1][2].

Product Specifications

CAS Number

1807367-80-1

Product Name Alternative

YM-529-d4

UNSPSC

12352005

Target

Apoptosis; Isotope-Labeled Compounds; P2X Receptor

Type

Isotope-Labeled Compounds

Related Pathways

Apoptosis; Membrane Transporter/Ion Channel; Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Solubility

10 mM in DMSO

Smiles

O=P(O)(O)C(P(O)(O)=O)(O)CC1=CN=C2N1C([2H])=C([2H])C([2H])=C2[2H]

Molecular Formula

C9H8D4N2O7P2

Molecular Weight

326.17

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Sato K, et al. A third-generation bisphosphonate, minodronic acid (YM529), successfully prevented the growth of bladder cancer in vitro and in vivo. Br J Cancer. 2006 Nov 20;95 (10) :1354-61.|[3]Tanaka M, et al. Minodronic acid induces morphological changes in osteoclasts at bone resorption sites and reaches a level required for antagonism of purinergic P2X2/3 receptors. J Bone Miner Metab. 2018 Jan;36 (1) :54-63.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Isoform

P2X2 Receptor; P2X3 Receptor

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

EG432825 (BC060995) Mouse Tagged ORF Clone
MG201943 10 µg

EG432825 (BC060995) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
Cfl2 (NM_007688) Mouse Tagged ORF Clone
MG201352 10 µg

Cfl2 (NM_007688) Mouse Tagged ORF Clone

Sign In for Pricing
View Details
Recombinant ANPR B Antibody
RC-16289-01 50 μL

Recombinant ANPR B Antibody

Sign In for Pricing
View Details
Recombinant ANPR B Antibody
RC-16289-02 100 µL

Recombinant ANPR B Antibody

Sign In for Pricing
View Details
Recombinant ANPR B Antibody
RC-16289-03 1 mL

Recombinant ANPR B Antibody

Sign In for Pricing
View Details
(3R)-3-Hydroxybutyric Acid-1-13C
TRC-H833028-10MG 10 mg

(3R)-3-Hydroxybutyric Acid-1-13C

Sign In for Pricing
View Details