Lactucin
Lactucin is an anti-inflammatory agent. Lactucin induces cancer cell apoptosis. Lactucin also shows analgesic, anticancer and antimalarial activities[1][2][3][4].
Product Specifications
CAS Number
1891-29-8
UNSPSC
12352005
Hazard Statement
H317
Target
Apoptosis; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Apoptosis
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/lactucin.html
Purity
99.72
Solubility
DMSO : ≥ 250 mg/mL
Smiles
OCC([C@]1([H])[C@]2([H])[C@]([C@H](CC(C)=C13)O)([H])C(C(O2)=O)=C)=CC3=O
Molecular Formula
C15H16O5
Molecular Weight
276.28
Precautions
H317
References & Citations
[1]Dang T, et al. Sesquiterpenoids with diverse carbon skeletons from the roots of Cichorium glandulosum and their anti-inflammatory activities. Fitoterapia. 2019 Jul;136:104170.|[2]Gromek D, et al. Biologically active preparations from Lactuca virosa L. Phytotherapy Research, 1992, 6 (5) : 285-287.|[3]Zhang F H, et al. Lactucin induces potent anti-cancer effects in HL-60 human leukemia cancer cells by inducing apoptosis and sub-G1 cell cycle arrest. Bangladesh Journal of Pharmacology, 2016, 11 (2) : 478-484.|[4]Bischoff TA, et al. Antimalarial activity of lactucin and lactucopicrin: sesquiterpene lactones isolated from Cichorium intybus L. J Ethnopharmacol. 2004 Dec;95 (2-3) :455-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
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Scientific Category
Natural Products
Clinical Information
No Development Reported
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