Paraxanthine
Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.
Product Specifications
CAS Number
[611-59-6]
UNSPSC
12352005
Hazard Statement
H302
Target
Drug Metabolite; Endogenous Metabolite
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Paraxanthine.html
Purity
99.97
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 70°C)
Smiles
O=C(N1C)NC2=C(N(C)C=N2)C1=O
Molecular Formula
C7H8N4O2
Molecular Weight
180.17
Precautions
H302
References & Citations
[1]Guerreiro S, et al. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol. 2008 Oct;74 (4) :980-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Phase 2
Isoform
Human Endogenous Metabolite; Microbial Metabolite
Available Sizes
Curated Selection
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