Paraxanthine

Paraxanthine, a caffeine metabolite, provides protection against Dopaminergic cell death via stimulation of Ryanodine Receptor Channels.

Product Specifications

CAS Number

[611-59-6]

UNSPSC

12352005

Hazard Statement

H302

Target

Drug Metabolite; Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/Paraxanthine.html

Purity

99.97

Solubility

DMSO : 25 mg/mL (ultrasonic; warming; heat to 70°C)

Smiles

O=C(N1C)NC2=C(N(C)C=N2)C1=O

Molecular Formula

C7H8N4O2

Molecular Weight

180.17

Precautions

H302

References & Citations

[1]Guerreiro S, et al. Paraxanthine, the primary metabolite of caffeine, provides protection against dopaminergic cell death via stimulation of ryanodine receptor channels. Mol Pharmacol. 2008 Oct;74 (4) :980-9.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Natural Products

Clinical Information

Phase 2

Isoform

Human Endogenous Metabolite; Microbial Metabolite

Available Sizes

Curated Selection

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