Anti-Acetylated Lysine Antibody
Rabbit Polyclonal Antibody specific to Acetylated Lysine
Product Specifications
CAS Number
9007-83-4
Product Name Alternative
Anti-Acetylated Lysine Rabbit Polyclonal Antibody
Host
Rabbit
Reactivity
All
Immunogen
Acetylated lysine-KLH conjugate.
Target
Acetylated Lysine
Clonality
Polyclonal
Type
Antibody
Applications
WB, ICC/IF, IP, ELISA
Field of Research
Neuroscience
Purification Method
Purified by Protein A affinity chromatography
Concentration
Lot Specific
Dilution
Dilute in PBS or medium that is identical to that used in the assay system.
Format
Purified
Form
Liquid
Buffer
Phosphate Buffered Saline
Additionnal Information
Immunoblotting: use at 1-2ug/mlELISA: use at 1-10ug/ml with acetylated lysine-containing proteins on the solid phase.
<br><br>These are recommended concentrations.
<br><br>End user should determine optimal concentrations for their applications.
Storage Conditions
This product is stable for at least 1 year at -20°C. Freeze in multiple aliquots to avoid repeated freeze-thaw cycles.
Specificity
This antibody recognizes proteins containing acetylated lysine residues. It does not recognize non-acetylated proteins.
Formulation
PBS, pH 7.0 and 50% glycerol.
Buffer pH
pH 7.0
Target Background
Post-translational modifications of proteins play critical roles in the regulation and function of many biological processes. A common post-transcriptional modification of lysine is acetylation. The conserved amino- terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs). Regulation of protein acetylation status is impaired in cancer and polyglutamine diseases, and HDACs have become promising targets for anti-cancer drugs currently in development.
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS2048170-01 0.1 mL
HRP-Linked Polyclonal Antibody to C Reactive Protein (CRP)
Sign In for Pricing
View Details MBS2048170-02 0.2 mL
HRP-Linked Polyclonal Antibody to C Reactive Protein (CRP)
Sign In for Pricing
View Details MBS2048170-03 0.5 mL
HRP-Linked Polyclonal Antibody to C Reactive Protein (CRP)
Sign In for Pricing
View Details MBS2048170-04 1 mL
HRP-Linked Polyclonal Antibody to C Reactive Protein (CRP)
Sign In for Pricing
View Details