Hyperelamine A

Hyperelamine A (compound 5) is a polycyclic polyprenylated acylphloroglucinols (PPAPs) . Hyperelamine A exhibits inhibitory activity against LPS-activated NO production in BV-2 cells via TLR-4/NF κB signaling[1].

Product Specifications

UNSPSC

12352005

Target

NF-κB

Type

Natural Products

Related Pathways

NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/hyperelamine-a.html

Solubility

10 mM in DMSO

Smiles

N/C(C1=CC=CC=C1)=C(C([C@@]2(C[C@H](C/C=C(C)\C)[C@]3(CC/C=C(C)/C)C)C)=O)/C([C@@]3(C2=O)C/C=C(C)/C)=O

Molecular Formula

C34H45NO3

Molecular Weight

515.73

References & Citations

[1]Jin-Yan Xi, et al. Discovery from Hypericum elatoides and synthesis of hyperelanitriles as α-aminopropionitrile-containing polycyclic polyprenylated acylphloroglucinols. Commun Chem. 2024, 7, 1.