Hyperelamine A
Hyperelamine A (compound 5) is a polycyclic polyprenylated acylphloroglucinols (PPAPs) . Hyperelamine A exhibits inhibitory activity against LPS-activated NO production in BV-2 cells via TLR-4/NF κB signaling[1].
Product Specifications
UNSPSC
12352005
Target
NF-κB
Type
Natural Products
Related Pathways
NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/hyperelamine-a.html
Solubility
10 mM in DMSO
Smiles
N/C(C1=CC=CC=C1)=C(C([C@@]2(C[C@H](C/C=C(C)\C)[C@]3(CC/C=C(C)/C)C)C)=O)/C([C@@]3(C2=O)C/C=C(C)/C)=O
Molecular Formula
C34H45NO3
Molecular Weight
515.73
References & Citations
[1]Jin-Yan Xi, et al. Discovery from Hypericum elatoides and synthesis of hyperelanitriles as α-aminopropionitrile-containing polycyclic polyprenylated acylphloroglucinols. Commun Chem. 2024, 7, 1.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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