N6-Methyladenosine-13C4

N6-Methyladenosine-13C4 (6-Methyladenosine-13C4; N-Methyladenosine-13C4) is 13C-labeled N6-Methyladenosine (HY-N0086) . N6-Methyladenosine is the most prevalent internal (non-cap) modification present in the messenger RNA (mRNA) of all higher eukaryotes. N6-Methyladenosine can modifies viral RNAs and has antiviral activities.

Product Specifications

Product Name Alternative

6-Methyladenosine-13C4; N-Methyladenosine-13C4

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite; Influenza Virus; Isotope-Labeled Compounds

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/n6-methyladenosine-13c4.html

Purity

99.8

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](O)[13C@H](N2[13CH]=NC3=C2N=[13CH]N=C3N[13CH3])O[C@@H]1CO

Molecular Formula

C7 13C4H15N5O4

Molecular Weight

285.24

Precautions

H302, H315, H319, H335

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Wang X, et al. N6-methyladenosine-dependent regulation of messenger RNA stability. Nature. 2014 Jan 2;505 (7481) :117-20.|[3]Li Y, et al. Genome-wide detection of high abundance N6-methyladenosine sites by microarray. RNA. 2015 Aug;21 (8) :1511-8.|[4]Dang W, et al. N6-Methyladenosine and Viral Infection. Front Microbiol. 2019 Mar 5;10:417.