SFNGGP-NH2
SFNGGP-NH2 is a biological active peptide. (PAR-3 is a high-affinity thrombin receptor. PAR-3 mRNA is expressed in the cutaneous mast cells of humans. Protease-Activated Receptors (PARs) have been studied for their roles in itch and their itch-associated response through histamine-dependent/independent pathways have been reported. PAR-3 has been shown not to induce itching alone but possibly in conjunction with PAR-4. Co-expression of PAR-3 and PAR-4 enhances thrombin action suggesting that PAR-3 alone does not mediate transmembrane signaling but instead functions as a cofactor to activate PAR-4.)
Product Specifications
CAS Number
261521-21-5
UNSPSC
12352209
Target
Protease Activated Receptor (PAR)
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sfnggp-nh2.html
Solubility
10 mM in DMSO
Smiles
OC[C@H](N)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(N)=O)C(NCC(NCC(N2[C@@H](CCC2)C(N)=O)=O)=O)=O)=O)=O
Molecular Formula
C25H36N8O8
Molecular Weight
576.60
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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