Frataxin-IN-1

Frataxin-in-1 (Compound (+) -11) is a Frataxin inhibitor with IC50 value of 45 μM, which can be used in the study of Friedreich's ataxia (FRDA) [1].

Product Specifications

CAS Number

[102616-64-8]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/frataxin-in-1.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=CC(=C1OC)C(C2=CC3=C(C=C2O)OCO3)N4CCOCC4

Molecular Formula

C20H23NO6

Molecular Weight

373.40

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Lavecchia A, et al. Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays. J Med Chem. 2013 Apr 11;56 (7) :2861-73.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

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