Frataxin-IN-1
Frataxin-in-1 (Compound (+) -11) is a Frataxin inhibitor with IC50 value of 45 μM, which can be used in the study of Friedreich's ataxia (FRDA) [1].
Product Specifications
CAS Number
[102616-64-8]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Ferroptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/frataxin-in-1.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=CC(=C1OC)C(C2=CC3=C(C=C2O)OCO3)N4CCOCC4
Molecular Formula
C20H23NO6
Molecular Weight
373.40
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Lavecchia A, et al. Discovery of a novel small molecule inhibitor targeting the frataxin/ubiquitin interaction via structure-based virtual screening and bioassays. J Med Chem. 2013 Apr 11;56 (7) :2861-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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