Ambelline
Product Specifications
UNSPSC Description
Ambelline is an alkaloid that can be isolated from the Amaryllidaceae family. Ambelline shows antimalarial activity against Dd2 P. falciparum strain, with an IC50 of 7.3 ± 0.3 μM[1][2].
Target Antigen
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ambelline.html
Smiles
O[C@H](C1)[C@]23C4=CC(OCO5)=C5C(OC)=C4C[N@]1[C@]2([H])C[C@@H](OC)C=C3
Molecular Weight
331.36
References & Citations
[1]Breiterová KH, et al. Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro. Pharmaceutics. 2023 Mar 21;15(3):1007. |[2]Ritomská A, et al. Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities. Saudi Pharm J. 2023 Aug;31(8):101684.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-119714/Ambelline-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-119714/
Clinical Information
No Development Reported
CAS Number
3660-62-6
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