Ambelline

Product Specifications

CAS Number

[3660-62-6]

UNSPSC Description

Ambelline is an alkaloid that can be isolated from the Amaryllidaceae family. Ambelline shows antimalarial activity against Dd2 P. falciparum strain, with an IC50 of 7.3 ± 0.3 μM[1][2].

Target Antigen

Parasite

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ambelline.html

Smiles

O[C@H](C1)[C@]23C4=CC(OCO5)=C5C(OC)=C4C[N@]1[C@]2([H])C[C@@H](OC)C=C3

Molecular Weight

331.36

References & Citations

[1]Breiterová KH, et al. Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro. Pharmaceutics. 2023 Mar 21;15(3):1007. |[2]Ritomská A, et al. Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities. Saudi Pharm J. 2023 Aug;31(8):101684.