PF 02367982
PF 02367982 is a potent and select progesterone receptor (PR) antagonist with an IC50 value of 47.3 nM. PF 02367982 has oral activity[1].
Product Specifications
CAS Number
913344-84-0
UNSPSC
12352005
Target
Progesterone Receptor
Type
Reference compound
Related Pathways
Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/pf-02367982.html
Smiles
O=C(NC)CN1N=C(C2CC2)C(OC3=CC=C(C#N)C=C3)=C1C4CC4
Molecular Formula
C19H20N4O2
Molecular Weight
336.39
References & Citations
[1]Alexander de Giorgio-Miller, et al. The translational pharmacology of a novel, potent, and selective nonsteroidal progesterone receptor antagonist, 2-[4- (4-cyano-phenoxy) -3,5-dicyclopropyl-1H-pyrazol-1-yl]-N-methylacetamide (PF-02367982) . J Pharmacol Exp Ther. 2008 Oct;327 (1) :78-87.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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