VK3-OCH3
VK3-OCH3 is a potent antitumor agent. VK3-OCH3 shows cytotoxicity for neuroblastoma cell lines and low cytotoxicity for normal cell lines. VK3-OCH3 induces apoptosis and cell cycle arrest at G2/M phase in IMR-32 cells. VK3-OCH3 shows antitumor activity[1].
Product Specifications
CAS Number
[255906-59-3]
UNSPSC
12352005
Hazard Statement
H302, H361, H372, H410
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vk3-och3.html
Purity
98.64
Solubility
10 mM in DMSO
Smiles
O=C1C(SCCOC)=C(C)C(C2=C1C=CC=C2)=O
Molecular Formula
C14H14O3S
Molecular Weight
262.33
Precautions
H302, H361, H372, H410
References & Citations
[1]Kitano T, et al. Vitamin K3 analogs induce selective tumor cytotoxicity in neuroblastoma. Biol Pharm Bull. 2012;35 (4) :617-23.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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