Aftin-4
Aftin-4 is an Amyloid-β42 (Aβ42) inducer.
Product Specifications
CAS Number
[866893-90-5]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Amyloid-β
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Aftin-4.html
Purity
98.44
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC[C@@H](NC1=NC(N(C)CC2=CC=CC=C2)=C3N=CN(C(C)C)C3=N1)CO
Molecular Formula
C20H28N6O
Molecular Weight
368.48
Precautions
H302, H315, H319, H335
References & Citations
[1]Meunier J, et al. Brain toxicity and inflammation induced in vivo in mice by the amyloid-β forty-two inducer aftin-4, a roscovitine derivative. J Alzheimers Dis. 2015;44 (2) :507-24.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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