(S, R, R) -VH032-CO-C3-CONH-C2-PEG3-OH
(S, R, R) -VH032-CO-C3-CONH-C2-PEG3-OH is an E3 ligase ligand-linker conjugate of PROTAC NCOA4 degrader-1 , which can be used for the synthesis of PROTACs[1].
Product Specifications
UNSPSC
12352005
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/s-r-r-vh032-co-c3-conh-c2-peg3-oh.html
Smiles
OCCOCCOCCOCCNC(CCCC(N[C@H](C(C)(C)C)C(N1[C@@H](C[C@H](C1)O)C(NCC2=CC=C(C=C2)C3=C(N=CS3)C)=O)=O)=O)=O
Molecular Formula
C35H53N5O9S
Molecular Weight
719.89
References & Citations
[1]Ji J, et al. Discovery of a NCOA4 Degrader for Labile Iron-Dependent Ferroptosis Inhibition[J]. Journal of Medicinal Chemistry, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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