Euxanthone
Euxanthone, a xanthone derivative, attenuates Aβ1-42-induced oxidative stress and apoptosis by triggering autophagy. Euxanthone exhibits anti-neoplastic and neuroprotective activities[1][2][3].
Product Specifications
CAS Number
[529-61-3]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Autophagy
Type
Natural Products
Related Pathways
Autophagy
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/euxanthone.html
Purity
98.0
Solubility
10 mM in DMSO
Smiles
O=C1C2=C(OC3=C1C=C(O)C=C3)C=CC=C2O
Molecular Formula
C13H8O4
Molecular Weight
228.20
Precautions
H315, H319
References & Citations
[1]Xiaodong Chen, et al. Euxanthone Impairs the Metastatic Potential of Osteosarcoma by Reducing COX-2 Expression. Anat Rec (Hoboken) . 2019 Aug;302 (8) :1399-1408.|[2]Wei Sun, et al. Euxanthone improves cognitive impairment by attenuating mitochondrial fragmentation and suppressing oxidative stress. Cent Eur J Immunol. 2021;46 (4) :446-455. |[3]aicheng Yuan, et al. Euxanthone Attenuates Aβ1-42-Induced Oxidative Stress and Apoptosis by Triggering Autophagy. J Mol Neurosci. 2018 Dec;66 (4) :512-523.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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