Nicardipine (hydrochloride) (Standard)

Nicardipine (hydrochloride) (Standard) is the analytical standard of Nicardipine (hydrochloride) . This product is intended for research and analytical applications. Nicardipine hydrochloride (YC-93) is a calcium channel blocker with an IC50 of 1 μM for blocking cardiac calcium channels. Nicardipine hydrochloride acts as an agent for chronic stable angina and for controlling blood pressure[1].

Product Specifications

CAS Number

[54527-84-3]

Product Name Alternative

YC-93 (Standard)

UNSPSC

12352005

Hazard Statement

H302, H400, H410

Target

Autophagy; Calcium Channel; Reference Standards

Type

Reference Standards

Related Pathways

Autophagy; Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/nicardipine-hydrochloride-standard.html

Purity

99.65

Smiles

O=C(C1=C(C)NC(C)=C(C(OCCN(C)CC2=CC=CC=C2)=O)C1C3=CC=CC([N+]([O-])=O)=C3)OC.[H]Cl

Molecular Formula

C26H30ClN3O6

Molecular Weight

515.99

Precautions

H302, H400, H410

References & Citations

[1]Charnet P, et al. Electrophysiological analysis of the action of nifedipine and nicardipine on myocardial fibers. Fundam Clin Pharmacol. 1987;1 (6) :413-31.|[2]R Stamatiou, et al. The dihydropyridine calcium antagonist nicardipine reduces aortic smooth muscle cell viability, proliferation and migration. Cardiovascular Research, 2018 Apr,114 (1) :S43.|[3]Sherrin H. Baky. Nic ardipine Hydrochloride.