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Onfekafusp alfa

Onfekafusp alfa (L19TNF) is a homotrimer that forms from engineered peptides for the L19 antibody in scFv format fused to human TNF. Onfekafusp alfa can be used for malignant glioma research[1][2].

Product Specifications

CAS Number

1957239-88-1

Product Name Alternative

L19TNF

UNSPSC

12352203

Target

TNF Receptor

Type

Inhibitory Antibodies

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/onfekafusp-alfa.html

Solubility

H2O

Smiles

[Onfekafuspalfa]

References & Citations

[1]Di Giacomo AM, et al. Immunotherapy for brain metastases and primary brain tumors. Eur J Cancer. 2023 Jan;179:113-120.|[2]Borsi L, et al. Selective targeted delivery of TNFalpha to tumor blood vessels. Blood. 2003 Dec 15;102 (13) :4384-92.

Shipping Conditions

Room temperature

Scientific Category

Inhibitory Antibodies

Clinical Information

Phase 3

Frequently Asked Questions

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