Kiss2 peptide
Kiss2 peptide is a positive regulator of reproduction. Kiss2 peptide binds with its cognate receptor Kiss2R (GPR54) in COS-7 cells, activates PKA and PKC signaling pathways through Gas and Gaq proteins, and thus enhances the activity of cAMP response element-dependent luciferase (CRE-luc) and serum response element-dependent luciferase (SRE-luc) [1].
Product Specifications
CAS Number
1111070-93-9
UNSPSC
12352209
Target
Kisspeptin Receptor; PKA; PKC
Type
Peptides
Related Pathways
Epigenetics; GPCR/G Protein; Stem Cell/Wnt; TGF-beta/Smad
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Endocrinology
Assay Protocol
https://www.medchemexpress.com/kiss2-peptide.html
Solubility
10 mM in DMSO
Smiles
O=C([C@@H](N)CC1=CC=CC=C1)N[C@H](C(N[C@H](C(N[C@H](C(N2[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CC3=CC=CC=C3)=O)CCCNC(N)=N)=O)CC(C)C)=O)=O)CC4=CC=CC=C4)=O)CCC2)=O)CC(N)=O)=O)CC5=CC=CC=C5)=O)CC(N)=O
Molecular Formula
C63H84N16O12
Molecular Weight
1257.44
References & Citations
[1]Wang B, et al., Inhibitory action of tongue sole LPXRFa, the piscine ortholog of gonadotropin-inhibitory hormone, on the signaling pathway induced by tongue sole kisspeptin in COS-7 cells transfected with their cognate receptors. Peptides. 2017 Sep;95:62-67.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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