Bucindolol
Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure[1].
Product Specifications
CAS Number
[71119-11-4]
UNSPSC
12352005
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Cardiovascular Disease; Endocrinology
Assay Protocol
https://www.medchemexpress.com/bucindolol.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
N#CC1=CC=CC=C1OCC(O)CNC(C)(C)CC2=CNC3=C2C=CC=C3
Molecular Formula
C22H25N3O2
Molecular Weight
363.45
References & Citations
[1]Liggett SB, et al. A polymorphism within a conserved beta (1) -adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Proc Natl Acad Sci U S A. 2006 Jul 25;103 (30) :11288-93.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
β adrenergic receptor
Available Sizes
Curated Selection
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