Bucindolol

Bucindolol is a β1-adrenergic receptor blocker, with intrinsic sympathomimetic activity, used in the research of heart failure[1].

Product Specifications

CAS Number

[71119-11-4]

UNSPSC

12352005

Target

Adrenergic Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Cardiovascular Disease; Endocrinology

Assay Protocol

https://www.medchemexpress.com/bucindolol.html

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CC1=CC=CC=C1OCC(O)CNC(C)(C)CC2=CNC3=C2C=CC=C3

Molecular Formula

C22H25N3O2

Molecular Weight

363.45

References & Citations

[1]Liggett SB, et al. A polymorphism within a conserved beta (1) -adrenergic receptor motif alters cardiac function and beta-blocker response in human heart failure. Proc Natl Acad Sci U S A. 2006 Jul 25;103 (30) :11288-93.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Isoform

β adrenergic receptor

Available Sizes

Curated Selection

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