Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Dazucorilant

Product Specifications

Product Name Alternative

CORT113176

UNSPSC Description

Dazucorilant (CORT113176) is a selective and high affinity non-steroidal glucocorticoid receptor (GR) modulator with a Ki value [1][2].

Target Antigen

Glucocorticoid Receptor

Type

Reference compound

Related Pathways

Immunology/Inflammation;Vitamin D Related/Nuclear Receptor

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/dazucorilant.html

Purity

98.91

Solubility

DMSO : 100 mg/mL (ultrasonic;warming;heat to 80°C)

Smiles

O=C(C1=CC=CC=N1)[C@@]23C(CCN(C3)S(=O)(C4=CC=C(C=C4)C(F)(F)F)=O)=CC5=C(C=NN5C6=CC=C(C=C6)F)C2

Molecular Weight

582.57

References & Citations

[1]Meyer M, et al. The Selective Glucocorticoid Receptor Modulator Cort 113176 Reduces Neurodegeneration and Neuroinflammation in Wobbler Mice Spinal Cord. Neuroscience. 2018;384:384-396.|[2]Pineau F, et al. New selective glucocorticoid receptor modulators reverse amyloid-β peptide-induced hippocampus toxicity. Neurobiol Aging. 2016;45:109-122.|[3]Canet G, et al. Central Role of Glucocorticoid Receptors in Alzheimer's Disease and Depression. Front Neurosci. 2018;12:739. Published 2018 Oct 16.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-132811/Dazucorilant-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-132811/Dazucorilant-SDS-MedChemExpress.pdf

Clinical Information

Phase 2

CAS Number

1496508-34-9

Available Sizes

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

UMPS (Phospho-Tyr37) Antibody
MBS9458476-01 0.05 mL

UMPS (Phospho-Tyr37) Antibody

Ask
View Details
UMPS (Phospho-Tyr37) Antibody
MBS9458476-02 0.1 mL

UMPS (Phospho-Tyr37) Antibody

Ask
View Details
UMPS (Phospho-Tyr37) Antibody
MBS9458476-03 5x 0.1 mL

UMPS (Phospho-Tyr37) Antibody

Ask
View Details
YBEY Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
50589061 1.0 µg DNA

YBEY Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)

Ask
View Details
Human LITAF (NM_004862) AAV Particle
RC203938A1V 250 µL

Human LITAF (NM_004862) AAV Particle

Ask
View Details
PCDHB15 CRISPRa sgRNA lentivector (set of three targets)(Mouse)
36145124 3 x 1.0μg DNA

PCDHB15 CRISPRa sgRNA lentivector (set of three targets)(Mouse)

Ask
View Details